Lectures – GM & Pharmacology

1st semester

1-2
Introduction : pathobiochemistry, clinical chemistry, laboratory diagnostics
Different levels of laboratory diagnostics (reference values, requesting test, interpretation of results)
3
Pathochemistry and laboratory signs of cell damage
4
Pathobiochemistry of inflammation
5
Laboratory aspects of investigating various disorders
6
Pathobiochemistry of plasma proteins
7
Inherited metabolic diseases and their laboratory diagnostics I
8
Inherited metabolic diseases and their laboratory diagnostics II
9
Inherited metabolic diseases and their laboratory diagnostics III
10-12
Clinical biochemistry of tumor metastasis
Pathobiochemical alterations in association with tumor growth and metastasis formation and their laboratory detection I
Pathobiochemical alterations in association with tumor growth and metastasis formation and their laboratory detection II
13
Tumor markers in the diagnosis of malignant diseases
14
Disorders of iron metabolism. Laboratory diagnostics of microcytic anemias
15
Laboratory diagnostics of hemoglobinopathies
16
Laboratory diagnostics of macrocytic and hemolytic anemias
17
Laboratory diagnostics of quantitative platelet disorders
18
Laboratory diagnostics of acut and chronic leukemias and lymphomas I

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19

Laboratory diagnostics of acut and chronic leukemias and lymphomas II

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20

Laboratory diagnostics of acut and chronic leukemias and lymphomas III

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21

ABO and Rh blood groups

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22

Other blood group systems (Kell, Kidd, Duffy, MNS, I)

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23

Compatibility testing. Transfusion reactions.

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24

History of blood transfusion, blood group serology. Blood products

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25
Laboratory diagnostics of central nervous system diseases. Laboratory investigation of the cerebrospinal fluid
26
Clinical biochemistry and laboratory diagnostics of porphyrias
27
Clinical biochemistry at the extremes of age
28-29
Therapeutic drug monitoring I
Therapeutic drug monitoring II
30
Disorders of vitamin metabolism

2nd semester

1
Coagulopathies (general introduction), haemophilias
2
Other coagulopathies, platelet function disorders
3
von Willebrand’s disease
4
Inherited thrombophilias
5
Acquired thrombophilias
6
Prethrombotic states, thromboembolism and DIC
7
Laboratory diagnostics of autoimmune diseases
8
Pathobiochemistry of the renal function I
Pathobiochemistry of the renal function II
9
Laboratory diagnostics of renal disorders
10
Disturbances of the acid-base balance
11-13
Disorders of sodium and water metabolism I
Disorders of sodium and water metabolism II
Disorders of sodium and water metabolism III
14-15
Disorders of potassium metabolism I
Disorders of potassium metabolism II
16
Pathogenesis and pathomechanism of diabetes mellitus
17
Laboratory diagnostics of diabetes mellitus
18
Pathobiochemistry and clinical biochemistry of the acute complications of diabetes mellitus
Hypoglycaemias
19
Hypoglycaemias
20
Disorders of lipid metabolism
21
Laboratory diagnostics of hyperlipidemia
22
Risk factors of atherosclerosis
23
Laboratory diagnostics of hyperuricaemia and gout
24-25
Laboratory diagnostics of acute coronary syndrome I
Laboratory diagnostics of acute coronary syndrome II
26-29
Pathobiochemistry of liver disorders I
Pathobiochemistry of liver disorders II
Laboratory diagnostics of liver disorders. Pathobiochemistry of acute hepatic disorders
Pathobiochemistry and laboratory diagnostics of cholestasis and cirrhosis
30
Pathobiochemistry and laboratory diagnosis of autoimmune liver diseases
31-33
Pathobiochemistry and laboratory diagnostics of the gastrointestinal tract I
Pathobiochemistry and laboratory diagnostics of the gastrointestinal tract II
34
Clinical biochemistry of hypothalamus and hypophysis
35-36
Pathobiochemistry of thyroid disorders
Laboratory diagnostics of thyroid functions
37
Clinical chemistry of parathyroid disorders
38
Disorders of calcium, phosphate and magnesium metabolism
39
Pathobiochemistry and laboratory diagnostics of adrenal cortex disorders
40
Pathobiochemistry and laboratory diagnostics of adrenal medulla disorders
41-42
Clinical biohemistry of gonadal functions I
Clinical biohemistry of gonadal functions II
43
Laboratory diagnostics of muscle disorders
44
Laboratory diagnostics of bone disorders
45.
Principles of clinical laboratory methods
46.
Minimum thematics
47.
Practical images